Urinary tract infection is defined as growth of a significant number of organisms. Occurrence of asymptomatic bacteriuria (ASB) in pregnant women is a major predisposition to the development of pyelonephritis, which is associated with significant maternal and fetal complications. Therefore, the present study was conducted to study microbial etiology and antibiotic susceptibility patterns of UTI in pregnancy. The study was designed as a hospital-based, prospective Observational study conducted at the Department of Obstetrics and Gynecology in Pt. J.N.M. Medical College and Dr. BRAM Hospital in Raipur, Chhattisgarh. The study spanned from July 2022 to August 2023. The study subjects included asymptomatic pregnant women identified with pus cells in the screening test (Urine routine microscopy) and symptomatic pregnant women seeking care. The statistical software namely SPSS 22.0 used for the analysis of the data. The majority of the patients were in the age group 26-30 years (40%) with mean age was 26.39 ±4.38 years. The maximum number of patients infected with E coli. (78.75%) The maximum number of patients among gram positive infection 95% had enterococcus. The antibiotic sensitivity among gram positive isolates showed that Enterococcus was maximum sensitive to Linezolid (100%). The present study underscores the critical importance of routine UTI screening during pregnancy. The majority of UTIs during pregnancy are caused by gram-negative bacteria such as E. coli.
Vijayakumar M. Revised Statement on Management of UTI. Indian Pediatrics. 2011;48:22-27.
Ko, K.S., Lee, M.Y., Song, J.H., Lee, H., Jung, S.J., and Jung, S.I. Prevalenceand characterization of extendedspectrum β-lactamase-producing Enterobacteriaceaeisolated in Korean hospitals. Diagn. Microbiol. Infect. Dis. 2008; 61: 453-459.
Duarte, G., Marcolin, A.C., Quintana, S.M., and Cavalli, R.C. Urinary tractinfection in pregnancy. Rev. Bras. Ginecol. Obstet. 2008; 30: 93-100.
Amiri M, Lavasani Z, Norouzirad R, Najibpour R, Mohamadpour M, Nikpoor AR,Raeisi M, Marzouni HZ. Prevalence of urinary tract infection among pregnant womenand its complications in their newborns during the birth in the hospitals of Dezful city,Iran, 2012-2013. Iranian Red Crescent Medical Journal. 2015 Aug;17(8):1-6.
Kant S, Lohiya A, Kapil A, Gupta SK. Urinary tract infection among pregnant womenat a secondary level hospital in Northern India. Indian journal of public health. 2017Apr 1;61(2):118-23.
Jolley, J.A., and Wing, D.A. Pyelonephritis in pregnancy: an update ontreatment options for optimal outcomes. Drugs. 2010; 70, 1643-1655.
MacLean, A.B. Urinary tract infection in pregnancy. Int. J. Antimicrob.Agents. 2001; 17, 273-276
Yeta KI, Michelo C, Jacobs C. Antimicrobial Resistance among Pregnant Women with Urinary Tract Infections Attending Antenatal Clinic at Levy Mwanawasa University Teaching Hospital (LMUTH), Lusaka, Zambia. Int J Microbiol. 2021 Mar 4; 2021:8884297.
Gowda T, Rajini M. Asymptomatic Bacteriuria and its Antibiotic Susceptibility Patterns among Pregnant Women in a Tertiary Care Center. J Med Sci Health 2021;7(1):38-42.
Thomas T, Tony RL, Thomas A, Santhosh SV, Gomathi M, Suresh A et al Antibiotic Resistance Pattern in Urinary Tract Infection during Pregnancy in South Indian Population. Asian Journal of Pharmaceutics. 2018 Apr-Jun;12(2): S625-S630.
Ahmed MA, Shukla GS, Bajaj HK. Incidence of Urinary Tract Infections and determination of their susceptibility to antibiotics among Pregnant Women. International Journal of Cell Science and Biotechnology. 2016 Jan; 5: 12-16.
Elzayat M, Vanes AB, Dabour M, Cheng F. Prevalence ofundiagnosed asymptomatic bacteriuria and associated risk factors during pregnancy: A cross sectional study at two tertiary centres in Cairo, Egypt. BMJ Open 2017;7:1-7.
Jalali M, Shamsi M, Roozbehani N, Kabir K. Prevalence of Urinary Tract Infection and Some Factors Affected in Pregnant Women in Iran Karaj City 2013. Middle-East J. Sci. Res. 2014; 20(7): 781-785.
Demilie T, Beyene G, Melaku S, Tsegaye W. Urinary bacterial profile and antibiotic susceptibility pattern among pregnant women in North West Ethiopia. Ethiopian journal of health sciences. 2012;22(2):11-17.
Dash M, Sahu S, Mohanty I, Narasimham MV, Turuk J, Sahu R. Prevalence, risk factors and antimicrobial resistance of asymptomatic bacteriuria among antenatal women. J Bas Clin Reprod Sci 2013;2:92-6.
Obirikorang C, Quaye L, Bio FY, Amidu N, Acheampong I, Addo K. Asymptomatic bacteriuria among pregnant women attending antenatal clinic at the University Hospital, Kumasi, Ghana. J Med Biomed Sci 2012;1:38-44.
Basu S, Sanyal A, Bhattacharyya K. A Clinico-microbiological Study of Urinary Tract Infections in Pregnant Women attending Antenatal Clinic of a Tertiary-level Hospital with Special Reference to Antimicrobial Sensitivity Pattern. Afro-Egyptian Journal of Infectious and Endemic Diseases. 2024 Mar 1;14(1):61-74.
Enayat K, Fariba F, Bahram N. Asymptomatic bacteriuria among pregnant women referred to outpatient clinics in Sanandaj, Iran. Int Braz J Urol 2007;34:699-707.
Celen S, Oruç AS, Karayalçin R, Saygan S, Unlü S, Polat B, et al. Asymptomatic bacteriuria and antibacterial susceptibility patterns in an obstetric population. ISRN Obstet Gynecol 2011;721872.
Sujatha R, Nawani M. Prevalence of Asymptomatic bacteriuria and its antibacterial susceptibility pattern among pregnant women attending the antenatal clinic at Kanpur, India. J Clin Diag Res 2014;8:1-3.
Oli AN, Okafor CI, Ibezim EC, Akujiobi CN, Onwunzo MC. The prevalence and bacteriology of asymptomatic bacteriuria among antenatal patients in the Nnamdi Azikiwe university teaching hospital Nnewi; South Eastern Nigeria. Niger J Clin Pract 2010;13:409-1.