International Journal of Pharma and Bio Sciences
 
 
    ISSN 0975-6299
www.ijpbs.net


ORIGINAL RESEARCH ARTICLE
Int J Pharm Bio Sci Volume 15 Issue 1, January - March, Pages:17-22

Prevalence of Hypothyroidism Among Pregnant Women

Dr Anekant Jain, Dr Rajeeb Kalita, Dr Anamika Kore and Shrikant Chandrakar
DOI: http://dx.doi.org/10.22376/Ijpbs.2024.15.1.b17-22
Abstract:

Thyroid disease is one of the commonest endocrine disorders affecting women of reproductive age group & henceconstitute the commonest endocrine disorder in pregnancy. It has long been seen that maternal thyroid hormone deficiency orexcess can further influence the outcome for the mother & fetus at all stages of pregnancy, as well as interfere with fertility &ovulation. Maternal hypothyroidism is the most common disorder of thyroid function in pregnancy & has been associated withfetal loss, miscarriage, preterm delivery, preeclampsia, low birth weight, placental abruption, fetal distress & reduced intellectualfunction of the offspring. Pregnancy is very delicate & it is necessary to be aware of the many factors that can further prevent ahealthy pregnancy. Awareness of such kinds of problems can lead to the prevention of many complications. Thyroid awareness inpregnancy can further prove to be a lifesaver for both mother & child. We assessed the Hospital Prevalence of hypothyroidismamong pregnant women who attended antenatal check-ups in obstetric clinics or were admitted to the obstetrics & gynecologydepartment due to some other obstetrics reasons. A cross-sectional study was done on 200 pregnant irrespective of age, parity,or socioeconomic status. Study subjects who are willing to participate in the study & gave written consent. In our study, weobserved that the prevalence of thyroid disorders, especially subclinical hypothyroidism (9.69%), overt hypothyroidism (2.55%) &total hypothyroidism (12.3%), was high. So, our study has paved the way for the acceptance of universal thyroid screening inpregnant women, especially in the Indian context.

Keywords: Hypothyroidism,Thyroid stimulating hormone, T3, T4,Thyroid screening.
Full HTML:
  1. Glinoer D. The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology. Endocr Rev. 1997;18(3):404-33. doi: 10.1210/edrv.18.3.0300, PMID 9183570.
  2. Casey BM, Leveno KJ. Thyroid disease in pregnancy. Obstet Gynecol. 2006;108(5):1283-92. doi: 10.1097/01.AOG.0000244103. 91597.c5. PMID 17077257.
  3. Casey BM, Dashe JS, Wells CE, McIntire DD, Byrd W, Leveno KJ, et al. Subclinical hypothyroidism & pregnancy outcomes. Obstet Gynecol. 2005;105(2):239-45. doi: 10.1097/01.AOG.0000152345.99421.22, PMID 15684146.
  4. Abalovich M, Gutierrez S, Alcaraz G, Maccallini G, Garcia A, Levalle O. Overt & subclinical hypothyroidism complicating pregnancy. Thyroid. 2002;12(1):63-8. doi: 10.1089/105072502753451986, PMID 11838732.
  5. Negro R, Formoso G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H. Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. J Clin Endocrinol Metab. 2006;91(7):2587-91. doi: 10.1210/JC.2005-1603, PMID 16621910.
  6. Haddow JE, Palomaki GE, Allan WC, Williams JR, Knight GJ, Gagnon J, et al. Maternal thyroid deficiency during pregnancy & subsequent neuropsychological development of the child. N Engl J Med. 1999;341(8):549-55. doi: 10.1056/NEJM199908193410801, PMID 10451459.
  7. Sahu MT, Das V, Mittal S, Agarwal A, Sahu M. Overt & subclinical thyroid dysfunction among Indian pregnant women & its effect on maternal & foetal outcome. Arch Gynecol Obstet. 2010;281(2):215-20. doi: 10.1007/s00404-009-1105-1, PMID 19437026.
  8. Velayutham K, Selvan SS, Unnikrishnan AG. Prevalence of thyroid dysfunction among young females in a south Indian population. Indian J Endocrinol Metab. 2015 Nov-Dec;19(6):781-4. doi: 10.4103/2230-8210.167546, PMID 26693428.
  9. Männistö T, Vääräsmäki M, Pouta A, Hartikainen AL, Ruokonen A, Surcel HM, et al. Thyroid dysfunction, and autoantibodies during pregnancy as predictive factors of pregnancy complications and maternal morbidity in later life. J Clin Endocrinol Metab. 2010 Jan 15;95(3):1084-94. doi: 10.1210/jc.2009-1904, PMID 20080846.
  10. Stagnaro-Green A, Glinoer D. Thyroid autoimmunity and the risk of miscarriage. Best Pract Res Clin Endocrinol Metab. 2004 Jun;18(2):167-81. doi: 10.1016/j.beem.2004.03.007, PMID 15157834. DOI: 10.1016/j.beem.2004.03.007.
[Download PDF]
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy
Pharmaceutical Fields
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Pharmaceutics
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Novel drug delivery system
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Nanotechnology
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Pharmacology
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Pharmacognosy
© Copyright 2009-2015 IJPBS, India. All rights reserved. Specialized online journals by ubijournal. Website by Ubitech Solutions
         Home I Contact I Terms & Conditions