Dhinodhar is the central hilly and dry deciduous area of Kachchh region of Gujarat. The ethnobotanical survey of this hill was conducted in the month of September-October. In the present study, a defined attempt has been made to document the indigenous knowledge of some medicinal plants of this region. The data reported was compiled through a fusion of interview with the local tribes. Some plants were found to have medicinal value and the tribal people largely depend on them for treating various types of ailments. The main plants of this hilly region consisting of Gando Bawal (Prosopis juliflora), Kherdi or Kherio-baval (Acacia senegol), Hanju (Melhania futteyporensis), Jar or Pilu (Salvadora persica), Sweet Gugal (Balesmodendron mukul), Lai (Tamarix gallica), etc. The ethnomedicinal value of 67 plant species belonging to 47 genera of 25 families were collected from this region.