Microsurgery is a general term for surgery requiring an operating microscope. Microsurgery is used to operate on very small structures, often requires miniaturized instruments, and has myriad uses. Microsurgery is used to reattach a severed hand or another amputated part to the body by reconnecting the small blood vessels and restoring the circulation before the tissue starts to die. The most obvious developments have been procedures developed to allow anastomosis of successively smaller blood vessels and nerves (typically 1 mm in diameter) which have allowed transfer of tissue from one part of the body to another and re-attachment of severed parts. Although microsurgery is used mostly in plastic surgery, microsurgical techniques are utilized by all specialties today, especially those involved in reconstructive surgery such as: general surgery, orthopedic surgery, gynecological surgery, otolaryngology, neurosurgery, maxillofacial surgery, and pediatric surgery. The aim of present article is to provide in depth knowledge about the technique of Microsurgery & its clinical utility.