Wound Healing Activity Of Alcoholic Extract Of "Guazumaulmifolia" Leaves On Albino Wistar Rats

Abstract

The alcoholic extract of Guazuma ulmifolia was evaluated for their wound healing activity in Albino Wistar rats using chemically induced wound model. The experimental animals were chemically burned by conc HCL (80%), and then divided into four groups, control, standard (Nitrofurazone 0.2% w/w), low dose (125 mg/kg) and high dose (250mg/kg). The re-epithelialization was evaluated by the reducing width of wounds for seven days. It was observed that the alcoholic extract showed re-epithelialization faster when compared with control. The extract also showed significant wound healing activity when compared with standard. The present results support that the use of alcoholic leaf extract of Guazuma ulmifolia in topical skin care and healing wounds.