Assay Of Clopidogrel By Visible Spectrophotometry

Authors

  • B.ANUPAMA K.V.S.R.Siddhartha college of pharmaceutical sciences, Vijayawada – 520 010, A.P, India.
  • V.JAGATHI K.V.S.R.Siddhartha college of pharmaceutical sciences, Vijayawada – 520 010, A.P, India.
  • A.APARNA K.V.S.R.Siddhartha college of pharmaceutical sciences, Vijayawada – 520 010, A.P, India.
  • M.MADHUBABU K.V.S.R.Siddhartha college of pharmaceutical sciences, Vijayawada – 520 010, A.P, India.
  • V.LAKSHMI ANNAPURNA K.V.S.R.Siddhartha college of pharmaceutical sciences, Vijayawada – 520 010, A.P, India.

Keywords:

Clopidogrel , Solochrome black T, Phenanthroline , potassium permanganate

Abstract

Three simple and sensitive spectrophotometric methods have been developed for the estimation of Clopidogrel (CLP) in pure and pharmaceutical dosage forms. This method is based on the formation of ion-pair complexes of the drug with acidic dye Solochrome black T (SBT : λmax 510 nm) , This method is  based on Oxidation of the drug with Phenanthroline (Fe(III)/PTL: λmax 515 nm) and This method is  based on oxidation followed by complex formation when the drug reacts with potassium permanganate (KMnO4 λmax 410nm). These methods have been statistically evaluated and found to be precise and accurate.

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Published

31.03.2011

How to Cite

B.ANUPAMA, V.JAGATHI, A.APARNA, M.MADHUBABU, & V.LAKSHMI ANNAPURNA. (2011). Assay Of Clopidogrel By Visible Spectrophotometry. International Journal of Pharma and Bio Sciences, 2(2`), 105–108. Retrieved from https://ijpbs.net/index.php/journal/article/view/748

Issue

Volume 2, Issue 2, 2011

Section

Research Articles

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