STUDY OF PROTEIN OXIDATION PRODUCTS AND ANTIOXIDANTS STATUS IN PRIMARY BRAIN TUMOR PATIENTS.

Authors

  • AMARESHWARA M Department of Biochemistry, Nitte University, KSHEMA, Mangalore.
  • GAYATRI M RAO Department of Biochemistry, Manipal University, KMC, Mangalore.
  • RAKESH M Department of Biochemistry, SDMC, Dharwar.
  • RAMESH Department of Biochemistry, RIMS, Raichur.
  • SAMEER Department of Biochemistry, Sikkim Manipal IMS, Gangtok, Sikkim..
  • SREEKANTHA Department of Biochemistry, Manipal University, KMC, Mangalore.

Keywords:

Primary brain tumor, Protein oxidation products,Antioxidants.

Abstract

Advanced oxidation protein product (AOPP) and protein carbonyl (PC) as protein oxidation products (PPP) and antioxidants such as reduced glutathione (GSH),total thiol (TT) and albumin levels were analyzed in 27 patients with diagnosed  primary brain tumor and 25 normal healthy age and sex matched controls. Statistically significant increased (p-0.001) levels of AOPP and PC were noted; GSH and TT levels were increased (p-0.833) & (p-0.032) respectively with decreased albumin levels (p-0.629).Hence increased oxidative stress signified by increased PPP and altered antioxidant levels may have a role in etipathogenesis of primary brain tumor. 

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Published

31.03.2011

How to Cite

AMARESHWARA M, GAYATRI M RAO, RAKESH M, RAMESH, SAMEER, & SREEKANTHA. (2011). STUDY OF PROTEIN OXIDATION PRODUCTS AND ANTIOXIDANTS STATUS IN PRIMARY BRAIN TUMOR PATIENTS. International Journal of Pharma and Bio Sciences, 2(1), 582–587. Retrieved from https://ijpbs.net/index.php/journal/article/view/732

Issue

Volume 2, Issue 1, 2011

Section

Research Articles

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