Comparison of Hemoglobin Levels Before and After Haemodialysis in Chronic Kidney Disease Patients

Abstract

Chronic Kidney Disease (CKD) is a progressive loss in renal function over 3 months of a year. CKD adversely affects the
haematopoietic system, the most common clinical manifestation being anaemia, which contributes to the morbidity and mortality of
the condition. Hemoglobin levels measured after hemodialysis, compared to those measured before hemodialysis, are suggested to
be a more accurate reflection of the hemoglobin levels between hemodialysis sessions and a better reference point for adjusting
erythropoietin dosing. Anaemia may be predictive of an increased risk of mortality in HD patients. The study compared various
haemoglobin before and after haemodialysis in chronic kidney disease patients in Tertiary Care Hospital. The present observational
study was carried out among 55 CKD patients admitted to the hospital for hemodialysis during the study period. Patients with
haematological malignancies, bleeding disorders, and unwillingness to participate were excluded. The collected data were analysed
with proper statistical methods. Out of 55 CKD patients, 43 were men, and 12 were women, with a mean age of 53.20 13.24 years.
51 to 70 years old comprised most of our study's age group. Pre-HD and post-HD hemoglobin levels had a p-value of 0.017. After
hemodialysis, the hemoglobin levels in post-HD patients fell with a statistically significant difference. (p<0.05). Monitoring hemoglobin
levels before and following hemodialysis may aid in avoiding any potential anaemia-related problems, lowering mortality and
morbidity. Although the current study has limitations, additional research is advised for definitive conclusions.