Antimicrobial efficacy of photosensitizers

Authors

  • Dr. Kanchana Sukumar Department of Periodontics, SRM dental college, Chennai-600089, Tamilnadu, India.
  • Dr. Anupama Tadepalli Department of Periodontics, SRM dental college, Chennai-600089, Tamilnadu, India.
  • Dr. Harinath.P Department of Periodontics, SRM dental college, Chennai-600089, Tamilnadu, India.
  • Dr. Deepa.P Department of Periodontics, SRM dental college, Chennai-600089, Tamilnadu, India.

Keywords:

photosensitizers, periodontitis, antimicrobial photosensitizers, toluidine blue, methylene blue.

Abstract

Inactivation of microorganisms using photodynamic therapy (PDT) has been defined as either antimicrobial photodynamic therapy (aPDT), Photodynamic antimicrobial chemotherapy (PACT) or photodynamic disinfection. Photodynamic therapy is a combination of nontoxic photosensitizer irradiated using visible light of appropriate wavelength, which in the presence of oxygen produces Reactive Oxygen Species (ROS). ROS is highly reactive and induces irreversible cytotoxic damage to the bacterial cell leading to the death of microorganisms. This review focuses on the various generations of photosensitizers and their antimicrobial effect against periodontal pathogens when used in periodontal and peri-implant disease management.

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Published

31.03.2020

How to Cite

Dr. Kanchana Sukumar, Dr. Anupama Tadepalli, Dr. Harinath.P, & Dr. Deepa.P. (2020). Antimicrobial efficacy of photosensitizers. International Journal of Pharma and Bio Sciences, 11(1), 119–128. Retrieved from https://ijpbs.net/index.php/journal/article/view/6799

Issue

Volume 11, Issue 1, 2020

Section

Review Articles

Categories

License

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