HISTOPATHOLOGICAL RESPONSES IN LIVER, KIDNEY, INTESTINE AND TESTIS OF ALBINO MICE AFTER EXPOSURE TO ALUMINIUM

Authors

  • N. JOHN SUSHMA Department of Biotechnology, Sri Padmavathi Mahila University, Tirupati-India
  • B. MAHITHA Department of Biotechnology, Sri Padmavathi Mahila University, Tirupati-India
  • P. L.SRAVANTHI Department of Biotechnology, Sri Padmavathi Mahila University, Tirupati-India
  • S. PRIYANKA Department of Biotechnology, Sri Padmavathi Mahila University, Tirupati-India
  • K. JAYANTHA RAO Department of Zoology, Sri Venkateswara University, Tirupati - 517 502-India

Keywords:

Aluninum acetate, Different tissues, Albino mice, Histological analysis.

Abstract

We have examined the effect of aluminum (Al) acetate  on albino mice. Different doses of aluminum acetate (3.5 mg/kg body weight (b.w), intraperitoneal injection., single dose:3.5mg/kg b.w, double dose:3.5 mg/kg  b.w, with 72 h interval on 1st and 4th day  and multiple doses: 3.5 mg/kg  b.w, with 72 h interval on 1st , 4th ,7th and 10th day)  resulted alterations in tissue histology of liver, kidney, intestine and testis. Our findings indicate that the pronounced pathological changes in multiple doses compared to double and single dose administered mice. We found that dose dependent exposure of aluminum acetate causes deleterious effects and make them less fit for better survival.    

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Published

31.03.2011

How to Cite

N. JOHN SUSHMA, B. MAHITHA, P. L.SRAVANTHI, S. PRIYANKA, & K. JAYANTHA RAO. (2011). HISTOPATHOLOGICAL RESPONSES IN LIVER, KIDNEY, INTESTINE AND TESTIS OF ALBINO MICE AFTER EXPOSURE TO ALUMINIUM. International Journal of Pharma and Bio Sciences, 2(1), 78–86. Retrieved from https://ijpbs.net/index.php/journal/article/view/659

Issue

Volume 2, Issue 1, 2011

Section

Research Articles

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