A review on nanosuspensions in drug delivery

Abstract

Nanotechnology has emerged as an tremendous field in the medicine.Nano refers to particles size   range  of 1-1000nm.Nanosuspensions are part of nanotechnology.Many of the drug candidates are exhibiting poor aqueous solubility. The use of drug nanosuspension is an universal formulation approach to increase the therapeutic performance of these drugs in any route of administration.A pharmaceutical nanosuspension is defined as very finely colloid,biphasic,dispersed, solid drug particles in an aqeous vehicle , size below 1µm ,without any matrix material , stabilized by surfactants and polymers, prepared by suitable methods for  Drug Delivery applications, through various routes of administration like  oral ,topical  ,parenteral ,ocular  and pulmanary  routes. This review article describes the preparation methods,characterization and applications of the nanosuspensions.