EFFICACY OF CEFOPERAZONE AND SULBACTAM AS A SURGICAL ANTIBIOTIC IN HIP SURGERY

Authors

  • P. V. INGLE Department of Clinical Pharmacy, R.C.Patel Institute of Pharmaceutical Education & Research, Shirpur-425405, Dist: Dhule, Maharashtra, India
  • J. P. ARAVADIYA B. Pharmacy Colloge, Navalgadh, Dist: Surendranagar, Gujarat, India.
  • S. D. PATIL Department of Clinical Pharmacy, R.C.Patel Institute of Pharmaceutical Education & Research, Shirpur-425405, Dist: Dhule, Maharashtra, India.
  • S. J. SURANA Department of Clinical Pharmacy, R.C.Patel Institute of Pharmaceutical Education & Research, Shirpur-425405, Dist: Dhule, Maharashtra, India.

Keywords:

Surgical site infection, hip surgery, prophylactic antibiotic, cefoperazone, sulbactam

Abstract

Surgical site infections (SSI’s) following hip surgery can lead to prolonged hospitalization,
increased morbidity and mortality and increased financial burden to patients. A total of 192
patients were enrolled in the study on the basis of inclusion and exclusion criteria. Surgical
site was monitored based on the guidelines issued by the Scottish Centre for Infection and
Environmental Health. The wound was checked on the 3rd, 6th, 12th and 30th days
postoperatively. Out of 192 enrolled patients, only 12 (6.25%) patients were found to be
affected with surgical site infection. Higher infection rate was found in patients with ASA
score > 2 (27.27 %), patients with risk index 2 (30.77 %), diabetic patients (19.05%) and
smoker patients (17.95 %). Also higher infection rate was found for surgery having longer
duration. Cefoperazone and sulbactam was found to be effective prophylactic antibiotic in
hip surgery.

Published

30.09.2010

How to Cite

P. V. INGLE, J. P. ARAVADIYA, S. D. PATIL, & S. J. SURANA. (2010). EFFICACY OF CEFOPERAZONE AND SULBACTAM AS A SURGICAL ANTIBIOTIC IN HIP SURGERY. International Journal of Pharma and Bio Sciences, 2(1), 211–219. Retrieved from https://ijpbs.net/index.php/journal/article/view/528

Issue

Section

Research Articles