SECONDARY METABOLITES FROM MANGROVE ENDOPHYTES: THEIR SIGNIFICANCE AGAINST CARBAPENEMASE RESISTANT ENTEROBACTERIACEAE – A REVIEW

Authors

  • R.NATHIYA Department of Biotechnology, School of Biosciences & Technology, VIT University, Vellore 632014, Tamil Nadu, India
  • GAYATHRI MAHALINGAM Department of Biotechnology, School of Biosciences & Technology, VIT University, Vellore 632014, Tamil Nadu, India

Keywords:

CRE, endophytes, secondary metabolites, novel drug.

Abstract

The emergence of Carbapenem-resistant Enterobacteriaceae (CRE) causes high mortality rate and is one of the most important medical issue worldwide including developing countries. The resistant pattern of CRE seems towards lactam antibiotics, including the third generation of cephalosporin except aztreonam and clavulanic acid due to the presence of resistance pattern in mobile genes. Consequently, we are in the urge to develop a new therapeutic drug against CRE to reduce the high mortality rate. Endophytes play an important role in developing a novel drug for various diseases. Recently, many researchers are working on endophytic fungi against multi-drug resistant strains to develop the novel drug. Therefore, the present review focuses on

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Published

30.09.2016

How to Cite

R.NATHIYA, & GAYATHRI MAHALINGAM. (2016). SECONDARY METABOLITES FROM MANGROVE ENDOPHYTES: THEIR SIGNIFICANCE AGAINST CARBAPENEMASE RESISTANT ENTEROBACTERIACEAE – A REVIEW. International Journal of Pharma and Bio Sciences, 7(3), 384–391. Retrieved from https://ijpbs.net/index.php/journal/article/view/5240

Issue

Volume 7, Issue 3, 2016

Section

Review Articles

Categories

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