EXPRESSION OF CALCITONIN GENE RELATED PEPTIDE (CGRP) IN SMALL NEURONS OF TRIGEMINAL GANGLION AND ITS IMPLICATIONS IN MIGRAINE

Authors

  • SANKARAN PK Associate Professor, Dept of Anatomy, Saveetha Medical College, Chennai.
  • JEEVAPRIYA .T Assistant Professor, Dept of Anatomy, Madha Medical College and Research Institute, Chennai.
  • VINAY JADHAV Professor, Dept of Radiology, Sri Lakshminarayana Institute of Medical Sciences, Pondicherry.

Keywords:

neuropeptide, migraine, small sized neurons.

Abstract

CGRP is a neuropeptide present in the central and peripheral nervous system that has diverse
functions as primary afferent neurotransmitter which is important in nociception. Migraine is a
neurovascular disorder involving trigeminal ganglion characterized by recurrent episodic headache
and a rise in levels of CGRP in plasma. In this study expression of CGRP was studied in neurons of
trigeminal ganglion in male wistar albino rats. CGRP is expressed in cytoplasm of neurons mainly in
the small sized neurons indicating that small sized neurons are involved in nociception.

Downloads

Published

30.06.2016

How to Cite

SANKARAN PK, JEEVAPRIYA. T, & VINAY JADHAV. (2016). EXPRESSION OF CALCITONIN GENE RELATED PEPTIDE (CGRP) IN SMALL NEURONS OF TRIGEMINAL GANGLION AND ITS IMPLICATIONS IN MIGRAINE. International Journal of Pharma and Bio Sciences, 7(2), 52–55. Retrieved from https://ijpbs.net/index.php/journal/article/view/5030

Issue

Volume 7, Issue 2, 2016

Section

Research Articles

Categories

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.