IN-VITRO SCREENING OF SOME MEDICINAL PLANTS ON BREAST, OVARY AND COLON CANCER CELL LINES.

Authors

  • ALLABAKASHA M. SHAIKH APT Research Foundation, Vadgaon Khurd, Pune (M.H.) 411041School of Pharmaceutical Sciences, Jaipur National University, Jaipur (Rajasthan), India.
  • DR. B. SHRIVASTAVA School of Pharmaceutical Sciences, Jaipur National University, Jaipur (Rajasthan), India.
  • DR. K. G. APTE APT Research Foundation, Vadgaon Khurd, Pune (M.H.) 411041
  • DR. P B. PARAB APT Research Foundation, Vadgaon Khurd, Pune (M.H.) 411041
  • DR. PANKAJ SHARMA School of Pharmaceutical Sciences, Jaipur National University, Jaipur (Rajasthan), India.
  • SAMPAT D. NAVALE BSDTAM Integrated Cancer Treatment and Research Center (ICTRC) Wagholi, Pune, (MH), India.
  • S. V. PAYGUDE APT Research Foundation, Vadgaon Khurd, Pune (M.H.) 411041

Keywords:

Human cancer cell lines; Invitro Cytotoxicity test; SRB assay; Indian medicinal plants.

Abstract

In the present study, the aqueous extracts of Curcum caesia, Curcuma longa, Curcuma zedoaria  and Gloriosa superba was studied for their in vitro cytotoxic activity against human breast cancer (MCF-7), colon cancer (HCT-116) and ovarian cancer (PA-1) cell lines using sulphorhodamine B (SRB) assay. The results showed that aqueous extract of Curcuma zedoaria and Gloriosa superba exhibited the prominent inhibitory effect whereas Curcuma longa and Curcuma caesia have moderate to weak effects in in vitro conditions as compared with standard drug 5-fluorouracil.

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Published

30.06.2016

How to Cite

ALLABAKASHA M. SHAIKH, DR. B. SHRIVASTAVA, DR. K. G. APTE, DR. P B. PARAB, DR. PANKAJ SHARMA, SAMPAT D. NAVALE, & S. V. PAYGUDE. (2016). IN-VITRO SCREENING OF SOME MEDICINAL PLANTS ON BREAST, OVARY AND COLON CANCER CELL LINES. International Journal of Pharma and Bio Sciences, 7(2), 11–17. Retrieved from https://ijpbs.net/index.php/journal/article/view/4973

Issue

Volume 7, Issue 2, 2016

Section

Research Articles

Categories

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