SYNTHESIS OF 2 – (1, 3 – SUBSTITUTED – 1 H- PYRAZOL-4-Y1) – 1H- BENZO (D) OXAZOLES BY USING AMMONIUM CHLORIDE; AS A MILD AND EFFICIENT CATALYST

Authors

  • CH.MADHU Department of Engineering Chemistry, AUCE (A), Andhra University, Visakhapatnam, Andhra Pradesh, India.
  • S.HARIPRASAD Department of Engineering Chemistry, AUCE (A), Andhra University, Visakhapatnam, Andhra Pradesh, India.
  • A.HYMAVATHI Department of Engineering Chemistry, AUCE (A), Andhra University, Visakhapatnam, Andhra Pradesh, India.
  • K.RAMANJANEYULU Department of Engineering Chemistry, AUCE (A), Andhra University, Visakhapatnam, Andhra Pradesh, India.
  • J.SANTHOSH KUMAR Department of Engineering Chemistry, AUCE (A), Andhra University, Visakhapatnam, Andhra Pradesh, India.
  • B.VENKATESWARA RAO Department of Engineering Chemistry, AUCE (A), Andhra University, Visakhapatnam, Andhra Pradesh, India.

Keywords:

Pyrazole aldehydes, 2-aminophenol, ammonium chloride, 1H- Benzo (d)oxazoles, Alzheimer’s disease.

Abstract

An efficient and simple procedure has been developed for the synthesis of 2- (1,3- substituted–1H- pyrazol–4-y1)–1H -benzo(d)oxazoles from the condensation of 3–Aryl-1- Phenyl –1H – pyrazole – 4- carabaldehyde with 2- aminophenol using ammonium chloride, which is a very inexpensive, metal free, readily available reagent. The target compounds were obtained in good yields under fairly mild reaction conditions at room temperature.

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Published

31.03.2016

How to Cite

CH.MADHU, S.HARIPRASAD, A.HYMAVATHI, K.RAMANJANEYULU, J.SANTHOSH KUMAR, & B.VENKATESWARA RAO. (2016). SYNTHESIS OF 2 – (1, 3 – SUBSTITUTED – 1 H- PYRAZOL-4-Y1) – 1H- BENZO (D) OXAZOLES BY USING AMMONIUM CHLORIDE; AS A MILD AND EFFICIENT CATALYST. International Journal of Pharma and Bio Sciences, 7(1), 257–260. Retrieved from https://ijpbs.net/index.php/journal/article/view/4865

Issue

Volume 7, Issue 1, 2016

Section

Research Articles

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