New Spectrophotometric Methods For The Determination Of Lornoxicam In Pharmaceutical Dosage Forms

Authors

  • E.VENUMADHAV Chief Operating Officer, Veeda CR, Ahmedabad,Gujarat (State),India.
  • T.NEEHA K.V.S.R Siddhartha college of Pharmaceutical Sciences, Vijayawada-520010, A.P., India.
  • P.BHARGAVI K.V.S.R Siddhartha college of Pharmaceutical Sciences, Vijayawada-520010, A.P., India.
  • AMREEN NISHAT K.V.S.R Siddhartha college of Pharmaceutical Sciences, Vijayawada-520010, A.P., India.
  • A.SWETHA K.V.S.R Siddhartha college of Pharmaceutical Sciences, Vijayawada-520010, A.P., India.
  • G.DEVALA RAO K.V.S.R Siddhartha college of Pharmaceutical Sciences, Vijayawada-520010, A.P., India.

Keywords:

ensitive visible spectrophotometric methods, Lornoxicam, oxidation of drug, complexation

Abstract

Two simple and sensitive visible spectrophotometric methods (A & B) for the determination of Lornoxicam (LOC) in bulk and pharmaceutical dosage forms are described. Method A is based on oxidation of drug with Ferric Chloride and subsequent complexation of Fe(II) with 2, 2' Bipyridine to form a blood red colored species ( λmax :520 nm).  Method B is based on oxidation of LOC with Ferric Chloride and chelation of Fe (II) with Bathophenanthroline to produce a blue colored chromogen (λmax: 610 nm). These methods were extended to the analysis of pharmaceutical formulations and results compared with the reference method.

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Published

31.12.2010

How to Cite

E.VENUMADHAV, T.NEEHA, P.BHARGAVI, AMREEN NISHAT, A.SWETHA, & G.DEVALA RAO. (2010). New Spectrophotometric Methods For The Determination Of Lornoxicam In Pharmaceutical Dosage Forms. International Journal of Pharma and Bio Sciences, 1(4), 491–494. Retrieved from https://ijpbs.net/index.php/journal/article/view/450

Issue

Volume 1, Issue 4, 2010

Section

Research Articles