AN INSIGHT FEATURES OF QUINOXALINE: A SHORT REVIEW

Abstract

 A quinoxaline also called a benzopyrazine in organic chemistry is heterocyclic compound containing a ring complex made up of a benzene ring and a pyrazine ring. It is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. Quinoxalines are used as dyes pharmaceuticals and antibiotics such as echinimycin, levemycin and actinoleutin. Some studies were carried out in order to explore the antitumoral properties of quinxaline compounds. Recently quinoxaline and its analogs have been investigated as the catalysti’s ligands. They can be formed by condensing ortho-diamines with 1,2- diketones. The parent substance of the group, quinoxaline results when glyoxal iscondensed with 1,2-diaminobenzene. Substituted derivatives arise when  α-ketonic acids, α-chlorketones, α-aldehyde alcohols and ketone alcohols are used in place of diketones. Quinoxaline and its analogues may also form by reduction of amino acids substituted 1,5 – difluoro -2, 4 – dinitrobenzene (DFDNB)