ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF ADENIUM OBESUM (DESERT ROSE) LEAF

Abstract

The parts of Adenium obesum (Desert rose) plant has been known to possess a wide range of biological activity consisting stems and roots. The purpose of present study was to ensure the presence of antibacterial activity in aqueous and alcoholic extracts of leaves of Adenium obesum. Antibacterial sensitivity test was done against Gram positive bacteria (Bacillus amyloliquefaciens and Staphylococcus aureus) and Gram negative bacteria (Pseudomonas aeruginosa and Escherichia coli) by Agar well diffusion method. Inhibition length was calculated and found to be maximum in alcoholic extract. Phytochemical screening was done in order to check the presence of active components in leaves of Adenium obesum. Result showed that methanolic extract has effective antibacterial activity against Gram positive bacteria and ineffective against Gram negative bacteria. The study suggest that leaves of Adenium obesum (Desert rose) plant can be used as an antimicrobial agent and expected that leaves of Adenium obesum may be used as therapeutic agents for various diseases.