HOMOCYSTEINE LEVELS IN DIABETIC PATIENTS WITH AND WITHOUT CARDIOVASCULAR DISEASE: A CROSS-SECTIONAL ANALYTICAL STUDY.

Authors

  • VANI AXITA CHANDRAKANT Assistant Professor, Department of Biochemistry, SDM College of Medical sciences and Hospital, Dharwad, India.
  • SANTOSH KUMAR Assistant Professor, Department of Community Medicine, Shimoga institute of Medical sciences and Hospital, Shimoga, India.
  • HEMANTH KUMAR R G Assistant Professor, Department of Forensic Medicine, SDM College of Medical sciences and Hospital, Dharwad, India.

Keywords:

Diabetes mellitus; Cardiovascular diseases; Total homocysteine; HPLC.

Abstract

Total Homocysteine (tHcy) levels are found to be significantly raised in patients suffering from cardiovascular diseases. In Non insulin dependent diabetes mellitus (NIDDM) cardiovascular disease (CVD) is one of the major macrovascular complications. The present study was conducted on a Goan population with an objective to evaluate the relation between the plasma tHcy in diabetic individuals with and without CVD. The one year cross sectional study comprised of 180 subjects, including 60 NIDDM individuals, 60 NIDDM individuals with CVD and 60 healthy controls. Plasma concentrations of tHcy levels were measured by High performance liquid chromatography (HPLC) in all study subjects. The data obtained was statistically analysed using student unpaired‘t’ test and comparison between the groups was done by analysis of variance. The tHcy levels were found to be significantly elevated in NIDDM and also in NIDDM with CVD in Goan Population.

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Published

30.06.2015

How to Cite

VANI AXITA CHANDRAKANT, SANTOSH KUMAR, & HEMANTH KUMAR R G. (2015). HOMOCYSTEINE LEVELS IN DIABETIC PATIENTS WITH AND WITHOUT CARDIOVASCULAR DISEASE: A CROSS-SECTIONAL ANALYTICAL STUDY. International Journal of Pharma and Bio Sciences, 6(2), 1361–1365. Retrieved from https://ijpbs.net/index.php/journal/article/view/4357

Issue

Volume 6, Issue 2, 2015

Section

Research Articles

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