ANTIMICROBIAL SCREENING OF METHANOLIC EXTRACT FROM VARIOUS PARTS OF CEROPEGIA BULBOSA AND CEROPEGIA ATTENUATA

Abstract

Ethnomedicine provides avenues for identification of compounds with antimicrobial properties and potential new antibiotics. The present studies focus on the antimicrobial activities of the crude methanolic extract of Ceropegia spp collected from Jaipur and Ajmer region of Rajasthan (India). Methanolic extracts of Ceropegia bulbosa and Ceropegia attenuata  were tested against four  common bacteria and two fungus as Proteus vulgaris (MTCC 1771), Staphylococcus aureus (MTCC 7443), Bacillus subtilis (MTCC 121), Fusarium solani (MTCC 9667), Trichophyton rubrus (MTCC 3272), Aspergillus niger (MTCC 3376) of medical importance using a quantitative agar well diffusion test and tube dilution assay. All plant extracts showed antimicrobial activities against the selected microorganisms; the methanol extracts in callus and tuber were most effective. The effectiveness against bacteria is more than fungus.  These results support the ethnomedicinal claim that Ceropegia spp is an effective treatment for microbes.