INSILICO DOCKING STUDIES OF THYMOQUINONE AS POTENTIAL ANTI TUMOR DRUG TARGET

Authors

  • TAHSEEN ALI Centre for Drug Discovery and Development, Sathyabama University, Chennai-600119
  • SHYAMALA KATRAGADDA Departments of Bioinformatics, Stella Maris College, Chennai 600086.
  • JERRINE JOSEPH Centre for Drug Discovery and Development, Sathyabama University, Chennai-600119.

Keywords:

Thymoquinone,Poloxime, Apoptotic proteins,Bioinformatics, Schrodinger

Abstract

Conventional cancer therapies cause serious side effects and, at best, merely extend the patient’s lifespan by a few years. Cancer control may therefore benefit from the potential that resides in alternative therapies. Hence, in this insilico study, we have attempted to perform docking studies of thymoquinone and poloxime with apoptotic proteins. A Glide score of -10 or lower usually represent good binding.The results demonstrate that the probable targets if validated in wet lab may provide insight into deciphering the mechanism of action

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Published

31.03.2015

How to Cite

TAHSEEN ALI, SHYAMALA KATRAGADDA, & JERRINE JOSEPH. (2015). INSILICO DOCKING STUDIES OF THYMOQUINONE AS POTENTIAL ANTI TUMOR DRUG TARGET. International Journal of Pharma and Bio Sciences, 6(1), 1038–1045. Retrieved from https://ijpbs.net/index.php/journal/article/view/4082

Issue

Volume 6, Issue 1, 2015

Section

Research Articles

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