EGFR EQUATIONS: EVALUATION AGAINST REFERENCE GFR IN INDIAN POPULATION

Authors

  • T. PAVANI KIRANMAI Departments of Biochemistry, Department of Nuclear Medicine, Nizam’s Institute of Medical Sciences, Hyderabad
  • SIRAJ AHMED KHAN Departments of Biochemistry, Department of Nuclear Medicine, Nizam’s Institute of Medical Sciences, Hyderabad.
  • K.S.S SAI BABA Departments of Biochemistry, Department of Nuclear Medicine, Nizam’s Institute of Medical Sciences, Hyderabad.
  • KAVITA NALLAPAREDDY Departments of Biochemistry, Department of Nuclear Medicine, Nizam’s Institute of Medical Sciences, Hyderabad.
  • PRISCILLA CHANDRAN. Departments of Biochemistry, Department of Nuclear Medicine, Nizam’s Institute of Medical Sciences, Hyderabad.

Keywords:

Reference GFR, Serum creatinine, Cockcroft-Gault equation, MDRD-equations

Abstract

Glomerular filtration rate (GFR) is the best overall index to measure and monitor kidney function. Older method to measure GFR by using Inulin was cumbersome and cannot be used in clinical practice. Serum creatinine based equations are the choice of GFR estimation in present clinical setting. In this study, we have compared the creatinine based equations with DTPA scan GFR (Reference GFR) measurements and found that serum creatinine based equations either underestimated or overestimated GFR. We found that Cockcroft –Gault equation was found to have least negative bias with reference GFR after adjustment for body surface area, followed by MDRD (6-Variable) equation.

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Published

31.03.2015

How to Cite

T. PAVANI KIRANMAI, SIRAJ AHMED KHAN, K.S.S SAI BABA, KAVITA NALLAPAREDDY, & PRISCILLA CHANDRAN. (2015). EGFR EQUATIONS: EVALUATION AGAINST REFERENCE GFR IN INDIAN POPULATION. International Journal of Pharma and Bio Sciences, 6(1), 621–626. Retrieved from https://ijpbs.net/index.php/journal/article/view/4036

Issue

Volume 6, Issue 1, 2015

Section

Research Articles

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