ANTIMUTAGENIC POTENTIAL OF AQUEOUS EXTRACT OF PEELS OF TUBERS OF Chlorophytum borivilianum SANTAPAU AND FERNANDES
Keywords:
Chlorophytum borivilianum, Ames assay, mutations, antimutagens, S9.Abstract
The present study was conducted to evaluate the antimutagenic properties of aqueous extract of peels of tubers of Chlorophytum borivilianum which are normally considered as wastes. The antimutagenic activity of an aqueous peel extract was evaluated by employing Ames assay commonly called as plate incorporation assay. Ames assay was conducted in two modes i.e. co-incubation and pre-incubation with and without metabolic activation system (S9) by taking strains of Salmonella typhimurium (TA98 and TA100). The aqueous peels extract showed statistically significant decrease in mutation frequency in both the strains against all the mutagens used in the experiments.
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