New Analytical Methods For The Estimation Of Racecadotril In Bulk And Pharmaceutical Formulations

Authors

  • E.VENUMADHAV Chief Operating Officer, VeedaCR, Ahmedabad,Gujarat(State)
  • AMREEN NISHAT KVSR Siddhartha College of Pharmaceutical Sciences,Vijayawada-520010.
  • T.NEEHA KVSR Siddhartha College of Pharmaceutical Sciences,Vijayawada-520010.
  • P.BHARGAVI KVSR Siddhartha College of Pharmaceutical Sciences,Vijayawada-520010
  • A.SWETHA KVSR Siddhartha College of Pharmaceutical Sciences,Vijayawada-520010
  • G. DEVALA RAO KVSR Siddhartha College of Pharmaceutical Sciences,Vijayawada-520010

Keywords:

Spectrophotometry, Racecadotril, Pharmaceutical preparations.

Abstract

Three simple and sensitive visible spectrophotometric methods (A-C) for the determination of Racecadotril in bulk and pharmaceutical formulations are described. They are based on the formation of colored species by treating with Folin-Ciocalteau (F.C) reagent under alkaline conditions (Method A, λmax: 742 nm) or 1, 10-phenanthroline (PTL) in the presence of ferric chloride (Method B, λmax: 510 nm) or 2, 2, -Bipyridine (BPN) in the presence of ferric chloride (Method C, λmax : 520 nm). These methods were extended to the analysis of pharmaceutical preparations and the results are compared with the reference method (USP). 

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Published

31.12.2010

How to Cite

E.VENUMADHAV, AMREEN NISHAT, T.NEEHA, P.BHARGAVI, A.SWETHA, & G. DEVALA RAO. (2010). New Analytical Methods For The Estimation Of Racecadotril In Bulk And Pharmaceutical Formulations. International Journal of Pharma and Bio Sciences, 1(4), 348–351. Retrieved from https://ijpbs.net/index.php/journal/article/view/394

Issue

Volume 1, Issue 4, 2010

Section

Research Articles