EFFECTS OF MAJOR DIETARY CONSTITUENTS ON ESTROUS CYCLE BY NON INVASIVE METHOD IN ALBINO MICE

Abstract

The aim of our present study is to assess the estrous cycle of mice fed refined high sugar diet (fructose), unrefined high sugar diet (palm jagerry), unrefined oil diet (unrefined sesame oil), refined oil (refined sesame oil) diet. Thirty Female albino mice of age, 21 days were randomly divided into five groups. The mice are fed unrefined high sugar diet, refined high sugar diet, unrefined oil diet, refined oil diet taps water ad libitum. The stage of the cyclist was determined by daily observation of vaginal smear. It was observed that mice fed high fructose diet shows significant decrease in the number of estrous cycle with concomitant significant increase in the duration of diestrus phase. Alterations in estrous cycle were also observed in metestrus and diestrus phases of unrefined and refined oil diet group mice. The present study concludes that mice fed refined high sugar diet exhibit irregular cycle.