SCREENING OF ANTIBACTERIAL ACTIVITY OF SOLANUM MELONGENA SEED EXTRACTS ON SELECTED HUMAN PATHOGENIC BACTERIA

Abstract

Antimicrobial efficiency of Solanum melongena seed extracts was examined using methanol, chloroform, acetone and petroleum ether, as solvents and tested against four human pathogenic bacteria such as Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Proteus vulgaris using Agar Well Diffusion Method. The phytochemical analysis of Solanum melongena seed was also made. The methanolic and acetone extract of Solanum melongena seed showed maximum inhibition against Staphylococcus aureus at all concentrations (75, 150 and 250 ug/ml) significant inhibition was proved at the higher concentration of petroleum ether extract while no inhibition was shown in the chloroform extract of Solanum melongena seed at any level of concentration against Staphylococcus aureus. The methanol extract of the Solonum melongena extract showed enormous inhibitory activity at all concentrations against Escherichia coli while the acetone and petroleum ether extracts of the same plant seed showed significant activity only at the higher concentration against Escherichia coli. The result of phytochemical analysis shows the presensce of reducing sugar, steroid, terpenoid and flavonoid in the seed extract of Solanum melongena.