VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR ANTAGONIST- A TARGET FOR TREATING INFLAMMATORY DISEASE

Authors

  • YADU NANDAN DEY Central Council for Research in Ayurveda and Siddha, Janakpuri, New Delhi, India
  • NEHA YADAV Roorkee College of Pharmacy, Kishanpur, Roorkee, Uttarakhand, India
  • MAHVISH JAMAL Roorkee College of Pharmacy, Kishanpur, Roorkee, Uttarakhand, India
  • KUMAR GHOSH Gupta College of Technological Sciences, Asansol, West Bengal, India

Keywords:

Angiogenesis, VEGF, Anti VEGF therapy, tumor, VEGF Receptor

Abstract

The present review of literature was done to check the influence of the main angiogenic factor
vascular endothelial growth factor in the various physiological and pathological conditions like growth,
development, tumor formation, arthritis etc. It was also seen that how VEGF are classified and
produced as well as the mechanism of action. VEGF bind over the specific receptors and cause
cascade of events of angiogenesis. So if the VEGF receptor antagonists are investigated they can
block the VEGF receptor and prevent the process of angiogenesis which occurs in various chronic
inflammations like solid tumor, rheumatic arthritis etc.

Downloads

Published

30.09.2010

How to Cite

YADU NANDAN DEY, NEHA YADAV, MAHVISH JAMAL, & KUMAR GHOSH. (2010). VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR ANTAGONIST- A TARGET FOR TREATING INFLAMMATORY DISEASE. International Journal of Pharma and Bio Sciences, 1(3), 1–8. Retrieved from https://ijpbs.net/index.php/journal/article/view/372

Issue

Volume 1, Issue 3, 2010

Section

Research Articles