THE EFFECT OF ARECA CATECHU. L EXTRACT ON STREPTOZOTOCIN INDUCED HYPERGLYCAEMIA IN WISTAR RATS

Abstract

To evaluate the antidiabetic property of aqueous Areca catechu extract, experimentation was studied in an animal model. The levels of blood glucose, plasma insulin and serum lipid profile were estimated and studied in streptozotocin diabetic rats. The findings were compared between normal, diabetic and Areca catechu extract treated diabetic rats. The findings indicated that the administration of the aqueous Areca catechu extract tended to bring the parameters significantly towards the normal. The effect of the aqueous Areca  catechu extract at a dose of 500 mg/kg body weight yielded a higher level of significance than the doses of 250 mg/kg body weight. Experiment suggested that Areca catechu extract had excellent effects on controlling the hyperglycemia and hyperlipidemia in diabetic rats.