EVALUATION OF IN VITRO ANTIMICROBIAL ACTIVITY OF NEW GENERATION POWERFUL DISINFECTANTS

Abstract

Disinfectants were tested for their inhibitory activities against commonly occurring
bacterial strains Acinetobacter baumannii, Escherichia coli, Pseudomonas aeruginosa,
Klebsiella pneumonia, Staphylococcus aureus and fungal strains like Candida albicans
and Aspergillus niger. The inhibition was recorded by measuring the zone of inhibition of
the disinfectants on the tested organisms. The results revealed that the disinfectants
Sepsonil DX Cream, Sarvodin, Povidone Iodine 7.5% Solution USP, Sterital, Sidol +
(Cetrimide and Chlorohexidine Gluconate), Sidol, Sterilhandz, Sepsonil DX, Microcleer +
Chlorhexidine Surgical Wash and Povidone-Iodine Cleaning Solution U.S.P. 10% w/v
Surgical Scrub were very effective as it inhibited the growth of Acinetobacter baumannii
(BAA-1605), Methicillin resistant Staphylococcus aureus (ATCC 43300), Escherichia coli
(ATCC 25922, ATCC 8739, BAA196, BAA198, BAA199, BAA 200, BAA 201 and BAA
457), Pseudomonas aeruginosa (BAA-2109), Klebsiella pneumonia (ATCC 51503),
Staphylococcus aureus (ATCC 6538) and Pseudomonas aeruginosa (ATCC 9027). Only
disinfectants Microcleer + Chlorhexidine Surgical Wash and Povidone-Iodine Cleaning
Solution U.S.P. 10% w/v Surgical Scrub were resulted antifungal activity against Candida
albicans (ATCC 10231) and Aspergillus niger (ATCC 16404).