ANTI DERMATOPHYTIC ACTIVITY ON ETHNOMEDICAL PLANTS USED BY A PRIMITIVE TRIBE "GADABAS" OF PADERU

Abstract

An attempt has been made to report antidermatophytic active on methanolic and ethyl acetate extracts of seven ethnomedicinal plants Adhatoda zeylanica medic (leaf), Argyrea nervosa Burn.F (fruit), Diplocyclos palmatus Linn. Jeffrey (fruit), Hoya pendula White & Arn (leaf), Paracalyx scariosa Roxb (Twig), Ricinus communis Linn (Root), Stemona Tuberosa Lour (Tuber) Used by Gadabas, a primitive group confining to Paderu, Visakhapatnam Dist, A.P.  Trichophyton rubrum is most prevalent species of Dermatophytes causing ring worm or tinea in and around Visakhapatnam out of all the plants tested Hoya pendula methanol extract, ethyl acetate extract showed significant zone of inhibition 27 mm and 28mm at 50µl  concentration and showed minimal inhabitation concentration (MIC) at 100µg in crude extracts. Further investigation is needed to identify the responsible compound which is present in Hoya pendula Leaf to develop a novel drug.