MICRO-DETERMINATION OF TADALAFIL IN PHARMACEUTICAL FORMULATIONS AND URINE SAMPLES OF DIABETIC PATIENTS TYPE-II IN TAIF AREA, SAUDIA ARABIA USING ATOMIC ABSORPTION AND ATOMIC EMISSION SPECTROMETRY

Authors

  • SABRY KH. MOHAMED Medical Laboratories Department, College of Applied Medical Sciences, Taif University, Taif 21944, P. O. Box 2425, KSA. Chemistry Department, Faculty of Science, Fayoum University, Fayoum, Egypt,
  • YOUSRI M. HUSSEIN Medical Laboratories Department, College of Applied Medical Sciences, Taif University, Taif 21944, P. O. Box 2425, KSA.Department of Medical Biochemistry, Faculty of Medicine, Zagazig University,Egypt.
  • BASSEM M. RAAFAT Medical Laboratories Department, College of Applied Medical Sciences, Taif University, Taif 21944, P. O. Box 2425, KSA.Genetic Engineering and Biotechnology Division Biophysics Group, National Research Center ,Cairo, Egypt.

Keywords:

Atomic emission, atomic absorption, ion-associate complexes, pharmaceutical analysis.

Abstract

New ion – associate complexes of tadalafil hydrochloride with [ Cadmium (II) and Zinc (II)] thiocyanates were precipitated and the excess unreacted metal complex was determined. A new method was given for the determination of tadalafil drug in pure solutions, in pharmaceutical formulations and urine samples of diabetic patients type – II  using atomic emission and atomic absorption spectrometry. The drug can be determined by the affort method in the range  0.32 - 160.65 μg mL-1.

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Published

30.06.2014

How to Cite

SABRY KH. MOHAMED, YOUSRI M. HUSSEIN, & BASSEM M. RAAFAT. (2014). MICRO-DETERMINATION OF TADALAFIL IN PHARMACEUTICAL FORMULATIONS AND URINE SAMPLES OF DIABETIC PATIENTS TYPE-II IN TAIF AREA, SAUDIA ARABIA USING ATOMIC ABSORPTION AND ATOMIC EMISSION SPECTROMETRY. International Journal of Pharma and Bio Sciences, 5(2), 285–291. Retrieved from https://ijpbs.net/index.php/journal/article/view/3470

Issue

Volume 5, Issue 2, 2014

Section

Research Articles

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