A COMPARISON OF in vitro FREE RADICAL SCAVENGING ACTIVITY OF FRESH AND DRY RHIZOMES OF Curcuma longa

Authors

  • MANOHARAN MOHANA Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore-641 043, Tamil Nadu, India.
  • PALGHAT RAGHUNATHAN PADMA Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore-641 043, Tamil Nadu, India.

Keywords:

Free radical scavenging - extracts - fresh and dry rhizomes - Curcuma longa.

Abstract

In the present study, the free radical scavenging activity of fresh and dry rhizomes of Curcuma longa was compared. The fresh and dry rhizomes of Curcuma longa were serially extracted into different solvents (petroleum ether, benzene, chloroform, ethyl acetate, methanol and water) of increasing polarity using a Soxhlet apparatus. The free radical quenching activity of the extracts were characterized against a battery of free radicals such as DPPH (1,1'-diphenyl-2-picryl hydrazyl), H2O2 (hydrogen peroxide), ABTS (2,2'-azino-bis-3-ethyl benzthiazoline-6-sulphonic acid), SO (superoxide), NO (nitric oxide) and OHâ— (hydroxyl), generated in vitro. The results obtained in the present study indicate that both fresh and dry rhizomes of Curcuma longa are more potent in scavenging free radicals in an effective way at a concentration of 10µg/ml.

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Published

30.09.2014

How to Cite

MANOHARAN MOHANA, & PALGHAT RAGHUNATHAN PADMA. (2014). A COMPARISON OF in vitro FREE RADICAL SCAVENGING ACTIVITY OF FRESH AND DRY RHIZOMES OF Curcuma longa. International Journal of Pharma and Bio Sciences, 5(4), 682–690. Retrieved from https://ijpbs.net/index.php/journal/article/view/3396

Issue

Volume 5, Issue 3, 2014

Section

Research Articles

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