ANTIBACTERIAL POTENTIAL OF ETHYLACETATE EXTRACT FROM THE LEAVES OF ELEPHANTOPUS SCABER LINN.

Abstract

In the present investigation, evaluation of the antibacterial potential of ethylacetate leaf extract at a concentration of (5,10,15 and 20µg/ml) of the plant species, Elephantopus scaber (Asteraceae) was carried out against certain Gram-positive bacteria (Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli, Proteus mirabilis and Vibrio cholerae) by disc diffusion and minimum inhibitory concentration methods. The ethylacetate leaf extract posses significant antibacterial activity at 20µg/ml against the tested bacteria. Furthermore, gram negative bacterial species Vibrio cholerae was found to be more sensitive as compared to gram positive. Therefore, the results obtained suggest that the ethylacetate leaf extract exhibited effective antibacterial compounds.