ANTIMICROBIAL RESISTANCE OF KLEBSIELLA PNEUMONIAE STRAINS FROM PATIENTS WITH URINARY TRACT INFECTIONS IN SBMPMC HOSPITAL BIJAPUR, INDIA.

Abstract

The resistance profile of the Klebsiella pneumoniae were left undone despite the increasing prevalence rate of this organism in urinary tract infections (UTI) and its role in antibiotic resistance. The   current study was undertaken to know the antibiotic sensitivity profile  of Klebsiella pneumoniae, isolated  from patients suffering from UTI in our medical college. The study was carried out  over a period of 3 years from  January 2010 to December 2012. Urine  specimens from both outpatients and inpatients of our hospital were processed. Females  were more frequently affected than males. (P>0.05 )  The most active antimicrobial  agent against K. pneumoniae were piperacillin-tazobactum  (72% sensitive), and  amikacin (61%). One  hundred and fifty two (97.4%) of all the isolates were multi-drug resistant. To conclude, this study stresses the importance of  prior knowledge of the sensitivity pattern of the pathogen , before prescribing an antimicrobial agent for a meaningful therapy and to avoid fast emergence of resis­tant mutants.