COMPARATIVE STUDY OF PROSTATIC DISEASES BY ESTIMATING SERUM PAP AND TOTAL PSA LEVELS

Authors

  • N.SRIDEVI Associate professor, Department of Bio chemistry, Guntur Medical College, Guntur – 522 004. A.P. India
  • M.JOJIREDDY Former professor and HOD, Department of Biochemistry, Guntur Medical College, Guntur – 522 004. A.P. India.

Keywords:

PSA, Serum PAP, BPH, Prostatic cancer.

Abstract

To compare prostatic diseases like BPH and Prostatic cancer by estimating the levels
of serum Prostatic Acid phosphatase (PAP) and total PSA levels.PSA is an extremely
useful tumour marker in prostatic diseases. In normal cases PSA ranges from 0-4ng/ml.
Values between 4-10ng/ml are seen in cases of BPH and above levels are seen in
prostatic cancer. Serum PAP was used as a tumour marker in 1938. Normal serum PAP
ranges from 0-5 K.A units/dl. Elevated levels can be seen in benign conditions like BPH
and also in malignant conditions like prostate cancer with and without metastasis. Total
PSA levels were estimated by ELISA and serum PAP levels were estimated by K.A
method. In our present study, significant elevation (p<0.001) of PSA was observed in
malignant tumours with>20ng/dl and in BPH around 10ng/ml. Serum PAP levels were
elevated in cases of BPH and prostatic cancer.

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Published

31.03.2014

How to Cite

N.SRIDEVI, & M.JOJIREDDY. (2014). COMPARATIVE STUDY OF PROSTATIC DISEASES BY ESTIMATING SERUM PAP AND TOTAL PSA LEVELS. International Journal of Pharma and Bio Sciences, 5(1), 782–787. Retrieved from https://ijpbs.net/index.php/journal/article/view/3192

Issue

Volume 5, Issue 1, 2014

Section

Research Articles

Categories

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