IN-VIVO AUTOFLUORESCENCE SPECTROSCOPY IN ORAL CANCER DIAGNOSIS: A SYSTEMATIC

Authors

  • Dr.V.JAYANTH KUMAR MDS Senior Lecturer, Department of Oral Medicine & Radiology, Saveetha Dental College, Saveetha University,Chennai, Tamil Nadu, India.
  • Dr.T.N.UMA MAHESWARI MDS Associate Professor, Department of Oral Medicine & Radiology, Saveetha Dental College, Saveetha University, Chennai, Tamil Nadu, India.

Keywords:

Autofluorescence spectroscopy, fluorophore, native fluorescence spectroscopy, oral cancer, non-invasive diagnosis

Abstract

Oral cancer remains a major health problem in South and South East Asian countries. Despite the therapeutic advancements, the 5 year disease free survival rate has been around 50% only. The main problems associated with poor prognosis are late diagnosis of cancer and recurrence of the cancer. This systematic review aims in the assessment of the reliability of autofluorescence spectroscopy in oral cancer diagnosis. Autofluorescence spectroscopy is a non-invasive diagnostic tool. It can assess the molecular level changes which affect the optical properties of tissues. In this review a total of 9 studies have been assessed for their diagnostic accuracy. The review shows that porphyrin as a fluorophore has a good potential in diagnosis of oral cancer.

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Published

31.03.2014

How to Cite

Dr.V.JAYANTH KUMAR MDS, & Dr.T.N.UMA MAHESWARI MDS. (2014). IN-VIVO AUTOFLUORESCENCE SPECTROSCOPY IN ORAL CANCER DIAGNOSIS: A SYSTEMATIC. International Journal of Pharma and Bio Sciences, 5(1), 252–260. Retrieved from https://ijpbs.net/index.php/journal/article/view/3124

Issue

Volume 5, Issue 1, 2014

Section

Review Articles

Categories

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