ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF ALLAMANDA CATHARTICA LINN.

Authors

  • K. HEMA Department of Chemistry, Saveetha School of Engineering, Saveetha University, Chennai-602 105
  • R. KRISHNAVENI Department of Chemistry, Saveetha School of Engineering, Saveetha University, Chennai-602 105

Keywords:

Allamanda Cathartic Linn., antibacterial, antifungal, E.coli, C.albicans.

Abstract

Fresh flowers of Allamanda Cathartica Linn. were collected and was extracted with 90% methanol under reflux. The alcoholic extract was concentrated in vacuo and the aqueous concentrate was fractionated with benzene, peroxide free diethylether and ethylacetate successively.  The ethyl acetate fraction was concentrated in vacuo and left in an ice chest for a few days. The yellow solid obtained, a quercitrin (quercetin 3-O-rhamnoside) derivative, was tested for its antibacterial and antifungal efficiencies against Staphylococcus aureus, Escherichia coli and strains of Candida albicans respectively. An explicit antibacterial effect was observed at 10μg concentration and as an antifungal agent at 800 μg.

Downloads

Published

31.03.2014

How to Cite

K. HEMA, & R. KRISHNAVENI. (2014). ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF ALLAMANDA CATHARTICA LINN. International Journal of Pharma and Bio Sciences, 5(1), 588–593. Retrieved from https://ijpbs.net/index.php/journal/article/view/3073

Issue

Volume 5, Issue 1, 2014

Section

Research Articles

Categories

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.