EFFECT OF PHYNETOIN SODIUM ON LIVER FUNCTION TESTS

Authors

  • DR KASHINATH GUMMA Associate Professor Department of Pharmacology, BRIMS BIDAR, KARNATAKA
  • DR GAJANAN P KULKARNI Assistant Professor Department of Pharmacology, BRIMS BIDAR, KARNATAKA

Keywords:

Phenytoin sodium, serum ALP, serum ALT, serum AST.

Abstract

Phenytoin sodium is the most commonly prescribed drug for the treatment of Grandmal epilepsy. The current study was conducted to evaluate the effect of Phenytoin sodium on liver function tests using serum AST, serum ALT, serum ALP as parameters. The results of the present study showed a significant increase in the levels of serum ALP in the epileptic patients on Phenytoin sodium as compared to control group. This increase in serum ALP could be a result of cholestasis induced by drug or as a consequence of hepatocellular toxicity.

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Published

31.03.2014

How to Cite

DR KASHINATH GUMMA, & DR GAJANAN P KULKARNI. (2014). EFFECT OF PHYNETOIN SODIUM ON LIVER FUNCTION TESTS. International Journal of Pharma and Bio Sciences, 5(1), 249–252. Retrieved from https://ijpbs.net/index.php/journal/article/view/3037

Issue

Volume 5, Issue 1, 2014

Section

Research Articles

Categories

License

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