EVALUATION OF GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS WITH AND WITHOUT MICROVASCULAR COMPLICATIONS

Abstract

Diabetes mellitus (DM) includes a group of metabolic disorders that share common phenotype of hyperglycemia. Assessing glycemia in diabetes has always been a challenge. Aim of this study is to evaluate glycemic control in patients with type 2 DM patients with and without microvascular complications. HbA1c, FBS and PP₂BS were estimated as measure of glycemic control. A cross sectional study consists of 150 subjects: 50 patients having type 2 DM without any microvascular complications (Group II), 50 patients with type 2 DM with one or more microvascular complications (Group III) and 50 normal healthy control (Group I) were selected. Study shows increased value of HbA1c, FBS and PP₂BS level in group II and group III patients compared to group 1 (higher than upper reference value in group III). These finding indicate that poor glycemic control plays important role in the pathophysiology and management of type 2 DM and its complications.