SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF 4-NITRO SCHIFF BASES

Authors

  • B.N.B.VAIDEHI Sri Sai Aditya Institute of Pharmaceutical Sciences and Research, Adb road, Surampalem, East Godavari District, Andhra Pradesh, India.
  • K.SURYA TEJASWI Sri Sai Aditya Institute of Pharmaceutical Sciences and Research, Adb road, Surampalem, East Godavari District, Andhra Pradesh, India.
  • N.V.PRABHAKAR Sri Sai Aditya Institute of Pharmaceutical Sciences and Research, Adb road, Surampalem, East Godavari District, Andhra Pradesh, India.
  • L.DEVI Sri Sai Aditya Institute of Pharmaceutical Sciences and Research, Adb road, Surampalem, East Godavari District, Andhra Pradesh, India.

Keywords:

antibacterial activity; antioxidant activity; DPPH; 4-Nitro aniline.

Abstract

The purpose of the research was to synthesize better antibacterial and antioxidant compounds using various substituted aromatic aldehydes for synthesis of 4-Nitro Schiff bases in the presence of glacial acetic acid as catalyst. The synthesized compounds were screened for antioxidant activity by DPPH method and antibacterial activity by Cup Plate method. The antibacterial activity was evaluated against four bacterial strains. IR spectroscopy and elemental analysis were used for characterization of compounds. Some of the synthesized compounds exhibited promising antioxidant and antibacterial activities.

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Published

31.12.2013

How to Cite

B.N.B.VAIDEHI, K.SURYA TEJASWI, N.V.PRABHAKAR, & L.DEVI. (2013). SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF 4-NITRO SCHIFF BASES. International Journal of Pharma and Bio Sciences, 4(4), 829–837. Retrieved from https://ijpbs.net/index.php/journal/article/view/2815

Issue

Volume 4, Issue 4, 2013

Section

Research Articles

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