AN INNOVATIVE GREEN SYNTHESIS OF SOME SCHIFF BASES AND THEIR ANTIMICROBIAL ACTIVITY

Authors

  • ANJALI JHA Department of Chemistry, GIS, GITAM University, Visakhapatnam, India
  • SHABANA YASHMEEN Department of Chemistry, GIS, GITAM University, Visakhapatnam, India
  • D N KUMAR Department of Chemistry, GIS, GITAM University, Visakhapatnam, India

Keywords:

amino benzoic acid/ pyridine, Schiff bases, ketone, benzaldehyde, ultrasonication, antimicrobial activity.

Abstract

An efficient, simple clean synthesis of Schiff bases of some aminobenzoic acid/ aminopyridine with ketone (acetyl acetone / cyclohexanone) and benzaldehyde were done by an ultrasound irradiation method as well as conventional method. The major advantages of ultrasonication are short reaction time, operational simplicity, high yield, easy workup and environment friendly procedure. The isolated compounds obtained from both the methods were compared and characterized by IR and NMR spectral data. These were screened against certain strains of bacteria and fungi and showed significant anti microbial activity.

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Published

31.12.2013

How to Cite

ANJALI JHA, SHABANA YASHMEEN, & D N KUMAR. (2013). AN INNOVATIVE GREEN SYNTHESIS OF SOME SCHIFF BASES AND THEIR ANTIMICROBIAL ACTIVITY. International Journal of Pharma and Bio Sciences, 4(4), 197–204. Retrieved from https://ijpbs.net/index.php/journal/article/view/2747

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Research Articles

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