SERUM URIC ACID, TRIGLYCERIDES, TOTAL CHOLESTEROL AND HDL-C MEASUREMENTS IN PRE-ECLAMPTIC WOMEN

Abstract

The present study has been undertaken to compare the maternal serum values of uric acid, triglycerides, total cholesterol and HDL-C between pre-eclamptic women and normotensive pregnant women. Study includes 80 women divided into two groups. Estimation of serum uric acid, triglycerides, total-cholesterol and HDL-C were analyzed by Modified Trinder Peroxidase, CHOD-PAP and Phosphotungstic acid precipitation method, using Erba Chem-5 plus semi-autoanalyser. Our results shows the mean maternal age and gestational age of group-I were statistically significant (p<0.05) than group-II. The systolic, diastolic blood pressure of group-I women were significantly higher than group-II women. Mean serum uric acid and triglycerides levels were significantly increased in group-I in comparison to group-II,p<0.05. There was no difference in the mean values of total-cholesterol between cases (group-I) and control (group-II), p>0.05; but the mean levels of HDL-C were significantly higher in group-II in compared to group-I, p<0.05. Women having pre-eclampsia had elevated levels of serum uric acid and altered triglycerides, total cholesterol and HDL-C values in maternal serum. These levels may have cause and effect relationship with these disorders.