EXPRESSION OF Π CLASS GLUTATHIONE-S-TRANSFERASES IN MICE LIVER UNDER THE INFLUENCE OF PARACETAMOL TREATMENT AND THE RECOVERY OF Π GSTS TO μ CLASS GLUTATHIONE-S-TRANSFERASES WITH HYBANTHUS ENNEASPERMUS (L.) F. MUELL. TREATMENT

Authors

  • S.HASEENA BHANU Dept of Biochemistry, Srivenkateswara University, Tirupati.A.P-517501.
  • K.THYAGARAJU Dept of Biochemistry, Srivenkateswara University, Tirupati.A.P-517501.

Keywords:

Hybanthus enneaspermus, Hepatoprotective effect, Expression of GSTs, Paracetamol.

Abstract

The present study was designed to investigate the expression of GSTs under the
influence of paracetamol and Hybanthus enneaspermus. Study with different substrates
of glutathione-s-transferases were done to know the expression of GSTs. Along with
this purification and isolation of GSTs were performed to know the expression of
subunits of liver GSTs.Three subunits were found. Newly π GSTs were expressed upon
treatment with paracetamol.In control liver μ GSTs are generally expressed. Hence the
selected plant Hybanthus enneaspermus showed the recovery of π into μ GSTs in the
case of liver.

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Published

30.09.2013

How to Cite

S.HASEENA BHANU, & K.THYAGARAJU. (2013). EXPRESSION OF Π CLASS GLUTATHIONE-S-TRANSFERASES IN MICE LIVER UNDER THE INFLUENCE OF PARACETAMOL TREATMENT AND THE RECOVERY OF Π GSTS TO μ CLASS GLUTATHIONE-S-TRANSFERASES WITH HYBANTHUS ENNEASPERMUS (L.) F. MUELL. TREATMENT. International Journal of Pharma and Bio Sciences, 4(3), 341–348. Retrieved from https://ijpbs.net/index.php/journal/article/view/2583

Issue

Volume 4, Issue 3, 2013

Section

Research Articles

Categories

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