ANTIANGIOGENIC ACTIVITY OF AQUEOUS EXTRACT OF CAMELLIA SINENSIS.

Authors

  • PAGE AMIT B. Department of Pharmacology, School of Pharmacy and Technology Management, NMiMS, Shirpur (M.S.), India
  • KULKARNI KALA S. Department of Pharmacology, School of Pharmacy and Technology Management, NMiMS, Shirpur (M.S.), India

Keywords:

Green tea, angiogenesis, CAM, mesenteric window, subcutaneous air pouch, Antiangiogenic.

Abstract

Leaves of Camellia sinensis (CS) have been used since ancient time and are believed to have a variety of beneficial effects on human body. Recent human studies have shown that green tea may contribute to reduce risk of cardiovascular diseases and cancers. However little is known about effect of whole extract on angiogenesis in animal models. In this work, we have demonstrated antiangiogenic effects of camellia sinensis extract on three different models of angiogenesis – Chicken Chorioallentoic Membrane assay (CAM), Subcutaneous air pouch in rat (SAC) and Mesenteric window angiogenesis in rat (MWA). The extract showed dose dependent reduction in blood vessel development and nature of newly formed vessels. These effects further suggest that whole extract of C. sinensis is useful as an herbal medicine for angiogenesis dependent diseases.

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Published

30.09.2013

How to Cite

PAGE AMIT B., & KULKARNI KALA S. (2013). ANTIANGIOGENIC ACTIVITY OF AQUEOUS EXTRACT OF CAMELLIA SINENSIS. International Journal of Pharma and Bio Sciences, 4(3), 995–1001. Retrieved from https://ijpbs.net/index.php/journal/article/view/2533

Issue

Volume 4, Issue 3, 2013

Section

Research Articles

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