EFFICACY OF TRANEXAMIC ACID IN SURGICAL MANAGEMENT OF VASCULAR MALFORMATIONS

Abstract

Surgical management of vascular malformations are one of the common cause of major blood loss .A  loss of 20%  of blood volume or more is defined as major loss . Severe bleeding often requires blood transfusion. Even when the benefits of transfusion outweighs the risk (eg: mismatched transfusion , allergic reaction, transmission of infections) strategies to minimize the use of limited resources such as blood products are essential.  Blood loss which is to a great extent where in no abnormality in surgery or hemostasis is found do require pharmacological management for hemostasis .The present study was conducted on 8 pateints (i.e 2 cases of arterio venous  malformations ,5 cases of venous malformation and 1 case of capillary malformation.)  admitted in Department of Plastic Surgery   at Narayana Medical college, Nellore. In all these cases tranexamic acid was used intra operatively and postoperatively and its efficacy was tested in minimizing blood loss and maintaining hemostasis.