ANTIDIABETIC EFFECT OF MALLOTUS PHILIPPINENSIS IN STREPTOZOTOCIN INDUCED DIABETIC RATS

Authors

  • V.NANDHINI Assistant Professor, Department of Biochemistry,CMS College of Science and Commerce, Coimbatore, India
  • DR. D. VICTOR AROKIA DOSS Associate Professor, Department of Biochemistry,PSG College of Arts and Science, Coimbatore, India.

Keywords:

Antidiabetic,Mallotusphilippinensis(MP),Hydroethanolicextract(HEE),treptozotocin (STZ), Insulin, Glycosylated haemoglobin

Abstract

In the present work the antidiabetic activity of the Mallotus philippinensis was evaluated. The hydroethanolic bark extract  showed significant increase in the levels of body weight, insulin and significant decrease in blood glucose,  and glycosylated  haemoglobin when administered orally for 30 days to STZ induced diabetic rats at a dose of 200 and 400mg/kg body weight. Phytochemical studies also revealed the presence of phenolics in the bark extract which may be responsible to exert antidiabetic activity. Hence it can be used as a drug for diabetes mellitus.

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Published

30.06.2013

How to Cite

V.NANDHINI, & DR. D. VICTOR AROKIA DOSS. (2013). ANTIDIABETIC EFFECT OF MALLOTUS PHILIPPINENSIS IN STREPTOZOTOCIN INDUCED DIABETIC RATS. International Journal of Pharma and Bio Sciences, 4(2), 653–658. Retrieved from https://ijpbs.net/index.php/journal/article/view/2339

Issue

Volume 4, Issue 2, 2013

Section

Research Articles

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