ANTIDIABETIC EFFECTS OF RICINUS COMMUNIS ON THE BLOOD BIOCHEMICAL PARAMETERS IN STREPTOZOTOCIN INDUCED ALBINO RAT

Authors

  • SEEMA MANN Department of Zoology, School of Life Sciences, Dr B. R. Ambedkar University, Agra, India.
  • P. K. SINGH Department of Zoology, School of Life Sciences, Dr B. R. Ambedkar University, Agra, India.
  • ANITA Department of Zoology, School of Life Sciences, Dr B. R. Ambedkar University, Agra, India.
  • ANIL KUMAR GUPTA Department of Zoology, School of Life Sciences, Dr B. R. Ambedkar University, Agra, India.

Keywords:

Streptozotocin, Ricinus communis, lipid profile, liver profile, insulin, glucose.

Abstract

The present investigation was carried out to evaluate the antidiabetic effects of Ricinus communis leaves extract on the streptozotocin induced diabetic rats. Oral administration to ethanolic leaves extract was given (200mg/kg body weight) for 7, 15, 30, 45 and 60 days respectively. The decreased cholesterol, HDL, LDL, triglyceride and insulin; while increased SGOT, SGPT, ALP, ACP and glucose after streptozotocin induction, however, increased and decreased significantly after Ricinus communis treatment respectively. The results clearly show that the extract of Ricinus communis potent hypoglycemic activity.

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Published

30.06.2013

How to Cite

SEEMA MANN, P. K. SINGH, ANITA, & ANIL KUMAR GUPTA. (2013). ANTIDIABETIC EFFECTS OF RICINUS COMMUNIS ON THE BLOOD BIOCHEMICAL PARAMETERS IN STREPTOZOTOCIN INDUCED ALBINO RAT. International Journal of Pharma and Bio Sciences, 4(2), 382–388. Retrieved from https://ijpbs.net/index.php/journal/article/view/2305

Issue

Volume 4, Issue 2, 2013

Section

Research Articles

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