MAREK'S DISEASE: THE NEVER ENDING CHALLENGE –A REVIEW

Authors

  • SMITHA SUDHAKAR Department of Biotechnology University of Kerala, Thiruvananthapuram, India
  • Dr. A. JAYAKUMARAN NAIR Department of Biotechnology University of Kerala, Thiruvananthapuram, India

Keywords:

Marek’s Disease, Marek’s virus, Glycoproteins, Vaccines, Poultry, Herpes virus

Abstract

Marek's disease virus is a highly oncogenic alpha-herpesvirus that induces Marek's disease, a lymphomatous disease in poultry which accounts for the huge economic loss every year. The virus has been an ever evolving strain with different pathotypes causing much concern because of possible interspecies transfer to humans. The existing vaccines may drive the pathogen to more and more virulence .So it is very particular that new recombinant vaccines or improved vaccines based on Herpes Virus of Turkey’s, that can hinder viral replication and egression, should be developed. Marek’s virus serves as a model for herpes virus induced cancer studies outside humans and when disarmed the virus itself is assumed to be the best vaccine against cancer of Herpes Simplex Viral origin.  

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Published

30.06.2013

How to Cite

SMITHA SUDHAKAR, & Dr. A. JAYAKUMARAN NAIR. (2013). MAREK’S DISEASE: THE NEVER ENDING CHALLENGE –A REVIEW. International Journal of Pharma and Bio Sciences, 4(2), 6–11. Retrieved from https://ijpbs.net/index.php/journal/article/view/2264

Issue

Volume 4, Issue 2, 2013

Section

Review Articles

Categories

License

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