ULTRA-VIOLET SPECTROPHOTOMETRIC METHOD FOR VALIDATION OF CARBOCISTEINE FROM BULK DRUG AND PHARMACEUTICAL FORMULATION

Authors

  • RELE RAJAN V. CENTRAL RESEARCH LABORATORY, D.G. RUPAREL COLLEGE, MAHIM , MUMBAI 400 016.
  • PATIL SACHIN S. CENTRAL RESEARCH LABORATORY, D.G. RUPAREL COLLEGE, MAHIM , MUMBAI 400 016.

Keywords:

Carbocisteine, 0.1N HCl

Abstract

A simple,  rapid, sensitive and precise UV spectrophotometric method have been developed for the estimation of carbocisteine from bulk drug and pharmaceutical formulation. In this method carbocisteine showed maximum absorbance at about 200.4 nm in 0.1N HCl. Beer’s law was followed in the concentration range of 10 to 140 μg/ ml. Regression equation was found to be      y = 0.0067 x – 0.0015  and coefficient of correlation was 0.9999 . The proposed method is accurate, sensitive, reproducible and useful for the estimation of   carbocisteine from bulk drug and pharmaceutical formulation.

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Published

30.06.2013

How to Cite

RELE RAJAN V., & PATIL SACHIN S. (2013). ULTRA-VIOLET SPECTROPHOTOMETRIC METHOD FOR VALIDATION OF CARBOCISTEINE FROM BULK DRUG AND PHARMACEUTICAL FORMULATION. International Journal of Pharma and Bio Sciences, 4(2), 847–851. Retrieved from https://ijpbs.net/index.php/journal/article/view/2237

Issue

Volume 4, Issue 2, 2013

Section

Research Articles

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